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ORTHOPEDICOrthopedic Stem Cell Protocols


Regenerative Medicine for Orthopedic DisordersThe Role of Stem Cell Clinical Research & Deployment

Stem Cell Clinical Research & Deployment - Orthopedic Disorders




The Clero Stem Cell Treatment Center protocols are in alignment with the Science News article which notes that stem cell therapies are a promising approach to musculoskeletal problems that is gaining more and more attention (as reported in a Science News article entitled, “Stem cell treatment spurs cartilage growth,” Science News, May 5, 2012; Vol.181 #9).

The Clero Stem Cell Treatment Center offers protocols and investigational use of Autologous Adult Adipose Derived Stem Cells (ADSC’s) for clinical research and deployment for numerous orthopedic disorders, inclusive of:





Degenerative Arthritis (DJD) & Trauma Knee Problems Shoulder Problems Hip Problems


Elbow Problems Hand Problems

These ADSC’s cells are derived from fat – an exceptionally abundant source of stem cells – that has been removed during our mini-liposuction office procedure. The source of the regenerative stem cells actually comes from stromal vascular fraction (SVF) – a protein rich segment from processed adipose tissue. Stromal vascular fraction contains a mononuclear cell line (predominantly autologous mesenchymal stem cells), macrophage cells, endothelial cells, red blood cells, and important growth factors that facilitate the stem cell process and promote their activity. Our technology allows us to isolate high numbers of viable cells that we can deploy during the same surgical setting.

The SVF – stem cell fraction are harvested, concentrated, then deployed back into the patient’s body via injection or intravenous infusion on an outpatient basis (often times both methods are used). The total procedure takes less than 2 hours. Not all orthopedic disorders respond to stem cell therapy, and each patient must be assessed individually to determine the potential for optimal results from this regenerative medicine process.

The Clero Stem Cell Treatment Center is committed not only to providing a high degree of quality care for our patients – but we are also highly committed to clinical stem cell research and the advancement of regenerative medicine.





Knee – Shoulder – Hip – Elbow – Hand Degenerative Joint Arthritis & Injuries

Arthritis affecting the Knee, Shoulder, Hip, Elbow and Hand is a form of degenerative joint disease that affects millions of Americans. Often times simple repetitive use, over a life-time of years, is sufficient to exacerbate degenerative joint disease or result in injury caused by repetitive trauma. Typically pain and anti- inflammatory medications are used to treat the symptoms; but ultimately such medications can become ineffective and problematic; then, surgery becomes an option. There are several alternatives to joint surgery and joint replacement surgery, such as injection of cartilage substitutes or steroids. Steroid injection is not favored as a viable long term treatment since the steroids actually damage local tissues over time.

At the Clero Stem Cell Treatment Center we exploit anti- inflammatory, immuno-modulatory and regenerative properties of adult stem cells to mitigate inflammatory and degenerative diseases, through use of our SVF (rich in mesenchymal stem cells and growth factors). Some, but not all, of our protocols combine the use of PRP autologous platelet rich plasma to optimize the effects of the SVF. The Clero Stem Cell Treatment Center harvesting and deployment protocol is performed under local anesthesia as an outpatient at the time of SVF harvesting and procurement. The entire cellular surgical procedure takes less than 2 hours. The SVF- stem cell preparation is deployed both into the joint and intravenously to maximize the anti-inflammatory, immuno- modulatory and regenerative properties of the adult stem cells harvested. Certain types of joint problems including significant cartilage and ligamentous injuries may not be amenable to regenerative stem cell therapy. It is important to evaluate each individual case to assess likelihood of success with attempting regenerative therapy.





Shoulder Injuries

Shoulder problems come from chronic pain from rotator cuff injuries and arthritis of joints of the shoulder disables millions of Americans; both conditions can result in chronic shoulder injuries. Common treatments for these conditions include medications for relieving pain and inflammation, steroid injections, physical therapy – and, when all else fails, surgery.

However, as noted above, stem cell therapies are a promising approach to musculoskeletal problems that is gaining more and more attention (as reported in a Science News article entitled, “Stem cell treatment spurs cartilage growth,” Science News, May 5, 2012; Vol.181 #9).

Certain types of shoulder joint problems including certain tendon problems and ligamentous injuries may not be amenable to cell therapy. It is important to evaluate each individual case to assess likelihood of success with attempting regenerative therapy.





Hip Injuries

Hip injuries are a common complaint, especially among older people. A lifetime of use wears down the cartilage that cushions and protects the joints. This may lead to degenerative joint disease that impairs mobility, function, and quality of life. Patients often turn to medications or steroid injections into the hip joints in an effort to delay hip replacement surgery for as long as possible. Steroid injection is not favored as a viable long term treatment since the steroids actually damage local tissues over time. Other medications only address the symptoms and not the underlying pathology. In the United States, there are approximately 325,000 hip replacement surgeries performed every year. Certain types of hip problems including certain fractures and injuries may not be amenable to cell therapy. It is important to evaluate each individual case to assess likelihood of success with attempting regenerative therapy. Although our regenerative medicine SVF stem cell procedure is considered investigational, according to the Telegraph, “New stem cell treatment ‘being used by patients to avoid hip replacements’.” (Science News, May 5, 2012; Vol.181 #9).





Elbow and Hand Problems

Elbow and Hand problems from arthritis of joints of the upper extremity is a form of degenerative joint disease that disables millions of Americans. Certain types of elbow and wrist joint problems may be amenable to SVF regenerative medicine stem cell therapies, however, some conditions, including certain tendon problems and ligamentous injuries may not be amenable to cell therapy. It is important to evaluate each individual case to assess likelihood of success with attempting regenerative therapy.





Spine Stem Cell Protocols
- The Role of Stem Cell Clinical Research & Deployment -
Stem Cell Clinical Research & Deployment
– Spine Disorders -

At the Clero Stem Cell Treatment Center we exploit anti- inflammatory, immuno-modulatory and regenerative properties of adult stem cells to mitigate inflammatory and degenerative diseases.

The Clero Stem Cell Treatment Center offers protocols and investigational use of Autologous Adult Adipose Derived Stem Cells (ADSC’s) for clinical research and deployment for numerous orthopedic disorders, inclusive of:

Spine Degenerative Arthritis (DJD)
Spine Degenerative Disc Disease



Spine Facet Arthropathy

These ADSC’s cells are derived from fat – an exceptionally abundant source of stem cells – that has been removed during our mini-liposuction office procedure. The source of the regenerative stem cells actually comes from stromal vascular fraction (SVF) – a protein rich segment from processed adipose tissue. Stromal vascular fraction contains a mononuclear cell line (predominantly autologous mesenchymal stem cells), macrophage cells, endothelial cells, red blood cells, and important growth factors that facilitate the stem cell process and promote their activity. Our technology allows us to isolate high numbers of viable cells that we can deploy during the same surgical setting.

The SVF – stem cell fraction are harvested, concentrated, then deployed back into the patient’s body via injection or intravenous infusion on an outpatient basis (often times both methods are used). The total procedure takes less than 3 hours. Not all spine disorders respond to stem cell therapy, and each patient must be assessed individually to determine the potential for optimal results from this regenerative medicine process.

The Clero Stem Cell Treatment Center is committed not only to providing a high degree of quality care for our patients – but we are also highly committed to clinical stem cell research and the advancement of regenerative medicine.

Cervical & Lumbar Spine Arthritis and Injuries

Spine pain, either in the cervical (neck) or lumbar (low back) spine regions, are typically associated with Degenerative Disk Disease and Facet Arthropathy (a type of arthritis). Not all disk problems are amenable to regenerative therapy and patient selection is very important to optimize outcomes. Many forms of spine pain are actually due to arthritis of the facet joints (small joints where vertebra connect to their adjacent neighboring vertebrae).

Neck and back pain and neck and back injuries are amongst the most common medical conditions which are evaluated by physicians across the United States. Symptoms range from a dull, constant ache, to sharp pain with specific movements, and numbness; most symptoms dissipate over time.

However, in many instances, unfortunately, spine injuries and spine arthritis become chronic, and they can make life miserable. The usual treatments for chronic back injuries (neck and bak), whether they’re caused by acute or repetitive injuries or degenerative osteoarthritis, or degenerative disc disease, include anti- inflammatory medications, physical therapy, and, in some cases, surgery.








The Clero Stem Cell Treatment Centers protocols with to Spine Arthritis and Spine disease that attempts to exploit the anti- inflammatory and healing effects of SVF (rich in mesenchymal stem cells and growth factors). The protocol uses an advanced method of target planning using MRI with gadolinium contrast to identify inflamed or degenerated areas along the cervical spine and lumbar spine. Once these are located, SVF is deployed by laser guided CAT scan to within 1mm of the targets as seen on MRI. This is all done as an outpatient at the time of SVF harvesting and procurement. The entire procedure takes approximately 3 hours. This unique targeting and deployment system is the only one like it in the world for deploying SVF into the spine.

The potential of this approach is garnering interest among scientists and patients alike, as discussed in Science News: “Stem Cell Therapy: A Future Treatment for Lower Back Pain?”

(University of Gothenburg (2010, November 29). Stem cell therapy: A future treatment for lower back pain?. Science Daily; T. Svanvik, H. Barreto Henriksson, C. Karlsson, M. Hagman, A. Lindahl, H. Brisby. Human Disk Cells from Degenerated Disks and Mesenchymal Stem Cells in Co-Culture Result in Increased Matrix Production. Cells Tissues Organs, 2010; 191 (1): 2 DOI: 10.1159/000223236).

Science News notes that treatment for these type of spinal conditions using stem cells may be an alternative to today’s surgical procedures. This is fortified by the finding that “images taken by MRI showed that the transplanted stem cells survived, that they developed into cells that had a function similar to that of disc cells, and that there was a certain degree of healing in the disc.” The advantage of such treatment over today’s surgical approaches is that it would be a much simpler and less serious procedure for the patient.

Contact Us

Address

Middle East
Bahrain

Zinj Manama

Doha | Qatar

Boston Medical Center Al Waab street Doha Qatar


USA
Beverly Hills Los Angeles California
Las Vegas Nevada

Dr. Pierre R. Clero MD.

US Number

+1 702 6054502

Bahrain
Faith Ocampo: Patient coordinator:

+973 36197919

DOHA | QATAR

+974 33861017